Galilei Donna did one thing right. No, two things! First of all, it took a one-trick premise and actually followed through on it. Usually when an anime has a premise that is built on just one concept or person or idea(in this case, the historical person Galileo Galilei), it’s either never brought up again after the first few episodes or often mentioned but never explained or expanded upon. Galilei Donna, however, took the gimmick all the way by actually having a time travel arc where Galileo himself actually shows up! The other thing the show did right was to cast Hiroshi Kamiya as a flamboyant Italian sky pirate.
I ended up watching all of Galilei Donna while it was airing, but I don’t know anyone else who did the same. The reason for this is most likely that it really was not a good show, and it never seemed like it was going to be one either. The first episode had some nice moments, but it also had the same flaws that the rest of the show ended up having: The cold opening – while pun-tastic – was so cold that I never really understood what it was about, the world was busy but poorly explained, and it was hard to relate to any of the characters. And above all, for some reason it all felt very artificial, like watching a puppet theatre where the puppeteers are fully visible the whole time.
To be honest, I don’t remember much more about the show, because for the most part it’s completely forgettable. I guess the OP is cool and the character designs are cute, but that’s about it. Galilei Donna could have been the worst show to air during almost any season since I started watching anime, but funnily enough it aired at the same time as Coppelion and, as you know, Coppelion easily takes the cake in the department of badness as far as my opinions are concerned. So, in conclusion, Galilei Donna was bad and forgettable, but at least it wasn’t Coppelion.